Cystic Fibrosis (CF)

Also known as “mucoviscidosis” the main reason for this is secretion of sticky like mucus (viscid) which is unable to lubricate and flow freely in the air way passages and intestines. Cystic Fibrosis is an inherited disease its tendency is chronic lung infection and an inability to absorb fats and other nutrients from food. Despite the wide range of treatments CF remains a serious and potentially fatal disorder, general CF patients are children and adolescents.

Some characteristics changes on Body Composition in Cystic Fibrosis (CF)

  Malnourished
  Low body Fat
  Weight lose
  Stunted growth
  Delay onset of puberty
  High Body density
  Limited physical activity and exercise
  Lose of Fat Free Mass
  Muscle wasting in clinical patients
  Low Bone mineral
  Change in Body Composition


Monitoring Body Composition

Malnourish, stunted growth, reduce body weight, delayed onset of puberty, and limited capacity of physical and exercise is typical in CF children and adolescents. CF patients tend to store less fat and have higher body density. This group tends to have lower Body bone minerals and bone density which appears to be related to the disease and nutritional status. Further more suffers of CF tend to have higher fracture rates.

Clinicians must assess body composition in this group in order to provide adequate nutritional support so that normal growth can be maintained in children with CF.

The routine use of Maltron Analysers as screening tool could help identify these diseases

TECHNICAL PAPERS

Azcue M, Fried M, Pencharz P B. Use of Bioelectrical Impedance Analysis to Measure Total Body Water in Patients with Cystic Fibrosis. Journal of Paediatric Gastroenterology and Nutrition. 1993; 16, N 4: 440-445

Azcue M, Fried M, Pencharz PB. Use of bioelectrical impedance analysis to measure total body water in patients with cystic fibrosis. J Pediatr Gastroenterol Nutr 1993 May;16(4):440-5. Comment in: J Pediatr Gastroenterol Nutr 1993 May; 16(4) :365-7.

Borowitz D, Conboy K. Are Bioelectric Impedance Measurements Valid in Patients with Cystic Fibrosis. Journal of Paediatric Gastroenterology and Nutrition. 1994; 18, N 4: 453-456

Lands L C, Gordon C, Baron O, Blimkie C J, Hanning R M, Jones N L, Moss L A, Webber C E, Wilson W M, Heigenhauser G J F. Comparison of 3 Techniques for Body Composition Analysis in Cystic Fibrosis - Journal of Applied Physiology. 1993; 75, N 1: 162-166

Newby M J, Keim N L, Brown D L. Body Composition of Adult Cystic Fibrosis Patients and Control Subjects As Determined by Densitometry, Bioelectrical Impedance, Total-Body Electrical Conductivity, Skinfold Measurements, and Deuterium Oxide Dilution. Am J Clin Nutr. 1990; 52(2): 209-213

Roulet M, Spicher V. Schaffner C. Schutz V. Bioelectrical impedance analysis for nutritional assessment in cystic fibrosis patients. In: Escobar H, Baquero F, Suarez L, editors. Clinical ecology of cystic fibrosis; 18th European Cystic Fibrosis Conference; 1993 Hay 21-26; Madrid, Spain. New York: Elsevier Science Publishers; 1993. p. 271-4. (International congress series; no. 1034).

Spicher, V., Roulet, M., Schaffner, C., & Schutz, Y. (1993). Bio-electrical impedance analysis for estimation of fat-free mass and muscle mass in cystic fibrosis patients. European Journal of Paediatrics, 152, 222-225.

Spicher V. Roulet M, Schaffner C, Schutz V. Bio-Electrical Impedance Analysis for Estimation of Fat-Free Mass and Muscle Mass in Cystic Fibrosis Patients. European Journal of Paediatrics. 1993; 152, N 3: 222-225

Steinkamp G, Ruhl IB, Huller MJ, Schmoll E, von den Hardt H. Increased resting energy expenditure in malnourished patients with cystic fibrosis. Acta Univ Carol [tied] (Praha) 199O;36(1-4):177-9.