|
Close correlation has been found between urinary
creatinine excretion and BCM. It is possible to predict creatinine
from
BioScan-916 values of BCM and from Plasma creatinine, thus avoiding
the necessity of the periodic collection of urine.
The gold
standards in
measurement of Glomerular Filtration Rate (GFR) are inulin Clearance or
radio isotopic method.
Due to practicality,
creatinine clearance (Ccr)
is commonly used to evaluate GFR.
Disadvantage & Source of Error
1. Precise timed collection of Urine
2. Measurement of Clearances
3. Different formulas to estimate Ccr and GFR from Plasma Creatinine
BioScan was used to estimate GFR in 177 adult
renal patients (100 female and 77 males) with different degrees of
renal
function.
GFR measured as the renal clearance of 99m TC-DTPA
ranged 4.4 - 242 ml/min. A significant linear correlation was
found.
GFR was predicted also according to Cockcroft and Gault
(CG-GFR) and MDRD formulas (MDRD-GFR)
BioScan-916 is simple and time saving method
of avoiding unnecessary collection of urine over 24hrs.
Estimation of GFR
is appropriate for the evaluation of renal function and progression of
Kidney disease (REFER TO PAPER)
|
